Objective To investigate the relationship between the digit ratio and coronary heart disease. Methods Use anthropometry, digit length of both hands in each person was measured. Digit ratios were counted and compared between right hands and left hands, for coronary heart disease patients and controls respectively. Results (1) Our results showed the trend as 2D∶3D<2D∶4D<3D∶4D<2D∶5D<4D∶5D<3D∶5D in both groups. (2)The mean values for digit ratio was higher in the patient group than that of the control group. Significant differences in digit ratio for 2D∶3D (left, EM>P/EM><0.05) and 2D∶4D(left, EM>P/EM><0.01: right, EM>P/EM><0.05) were abserved between patients and controls. (3) We have shown a negative relation between the digit ratio and the onset age of coronary heart disease in Ningxia Han males(EM>P/EM><0.001). Conclusion Digit rati