Objective To investigate the relationship between digital dermaglyphic patterns of hands and breast cancer. Methods Using anthropometry,the frequency of finger print patterns of 224 women from Ningxia Han nationality (breast cancer and control sample ,112 each) were studied. The differences of them were also analyzed. Results Breast cancer patients had higher digital frequencies of whorls in both hands as compared with that of controls, and it showed a significant differences(EM>P/EM><0.001). The digressive order of both groups was Ⅳ> I> II> III> V. The frequency of 6 or more digital whorls in breast cancer was higher than that of the controls, and it also showed significant differences (EM>P/EM><0.01). Conclusion The frequency of digital whorls (W) may be one of the important early diagnosis markers of breast cancer.