［1］ Zhang JS, Hou YL, Lu WW, et al. Intermedin1-53 protects against myocardial fibrosis by inhibiting endoplasmic reticulum stress and inflammation induced by homocysteine in apolipoprotein e-deficient mice［J］. J Atheroscler Thromb, 2016, 23(11):1294-1306.
［2］ Chang YY, Wu YW, Lee JK, et al. Effects of 12 weeks of atorvastatin therapy on myocardial fibrosis and circulating fibrosis biomarkers in statin-na?ve patients with hypertension with atherosclerosis［J］. J Investig Med, 2016, 64(7):1194-1199.
［3］ Pan G, Kou L, Wu Y, et al. Regulation of lipoprotein-associated phospholipase A2 silencing on myocardial fibrosis in mice with coronary atherosclerosis［J］. Biochem Biophys Res Commun, 2019, 514(2):450-455.
［4］ Zhao J, Wang JX, Li XY, et al. Effect of urantide on thoracic aorta injury in experimental atherosclerotic rats［J］. Journal of Jilin University (Medical Edition), 2013,39(4):653-656,863. (in Chinese)
赵娟,王佳昕,李雪燕,等.urantide对实验性动脉粥样硬化大鼠胸主动脉损伤的影响［J］.吉林大学学报(医学版), 2013, 39(4):653-656,863.
［5］ Zhao J,Yu QX,Kong W,et al. The urotensin Ⅱ receptor antagonist, urantide, protects against atherosclerosis in rats［J］. Experimental and therapeutic medicine, 2013, 5(6):1765-1769.
［6］ Huang ZY, Yang PY, Almoofti MR, et al. Comparative analysis of the proteome of left ventricular of heart atherosclerosis in rat［J］. Life Sci, 2004, 75(26):3103-3115.
［7］ Jiao YB, Rui YC, Li TJ, et al. Expression of pro-inflammatory and anti-inflammatory cytokines in brain of atherosclerotic rats of effects Ginkgo biloba extract［J］. Acta Pharmacol Sin, 2005, 26(7):835-839.
［8］ Sun XX, Wang T, Cui HP, et al. Effects of urantide on serum calcium, blood lipid and myocardial enzymes in atherosclerotic rats［J］. Journal of Jilin University (Medical Edition), 2019,45(2):331-335,472. (in Chinese)
孙晓旭,王途,崔海鹏,等.urantide对动脉粥样硬化大鼠血钙、血脂和心肌酶学指标的影响［J］.吉林大学学报(医学版),2019,45(2):331-335,472.
[9］ Ambale-Venkatesh B, Liu CY, Liu YC, et al. AS sociation of myocardial fibrosis and cardiovascular events: the multi-ethnic study of atherosclerosis ［J］. European heart journal cardiovascular Imaging, 2019, 20(2):168-176.
［10］ Ghonim S, Voges Ⅰ, Gatehouse PD, et al. Myocardial architecture, mechanics, and fibrosis in congenital heart disease［J］. Front Cardiovasc Med, 2017, 4:30.
［11］ Bu H, Li YL, Lai MD, et al. Pathology［M］. Beijing: People’s Medical Publishing House, 2018:160. (in Chinese)
步宏, 李一雷, 来茂德, 等. 病理学［M］. 北京:人民卫生出版社, 2018:160.
［12］ Pollard CM, Desimine VL, Wertz SL, et al. Deletion of osteopontin enhances β2-adrenergic receptor-dependent anti-fibrotic signaling in cardiomyocytes［J］. Int J Mol Sci, 2019, 20(6):1396-1408.
［13］ Zhao H. Inhibition of osteopontin expression in myocardium reduces ventricular remodeling in mice with dilated cardiomyopathy and focal adhesion kinase mediates osteopontin induced secretion of type Ⅰ collagen fibers by cardiac fibroblasts［D］. Beijing: Peking Union Medical College, 2016. (in Chinese)
赵辉. 抑制心肌组织骨桥蛋白的表达减轻扩张型心肌病小鼠心室重构以及黏着斑激酶介导骨桥蛋白诱导心脏成纤维细胞分泌Ⅰ型胶原纤维的研究［D］.北京: 北京协和医学院,2016.
［14］ Meng G, Zhu J, Xiao Y, et al. Hydrogen Sulfide Donor GYY4137 Protects against Myocardial Fibrosis［J］. Oxid Med Cell Longev, 2015, 2015:691070.
［15］ Pearson D, Shively JE, Clark BR, et al. Urotensin Ⅱ: a somatos-tain-like peptide in the caudal neurosecretory system of fishes［J］. Proc Natl Acad Sci USA, 1980, 77(8): 5021-5024.
［16］ Tzanidis A, Hannan RD, Thomas WG, et al. Direct actions of urotensin Ⅱ on the heart: implications for cardiac fibrosis and hypertrophy［J］. Circ Res, 2003, 93(3):246-253.
［17］ Ban Y, Watanabe T, Suguro T, et al. Increased plasma urotensin-Ⅱ and carotid atherosclerosis are associated with vascular dementia［J］. J Atheroscler Thromb, 2009, 16(3): 179-187.
［18］ Papadopoulos P, Bousette N, Alramli W, et al. Targeted overexpression of the human urotensin receptor transgene in smooth muscle cells: effect of UT antagonism in ApoE knockout mice fed with Western diet［J］. Atherosclerosis, 2009, 204(2): 395-404.
［19］ Zhao J, Xie LD, Song CJ, et al. Urantide improves atherosclerosis by controlling C-reactive protein, monocyte chemotactic protein-1 and transforming growth factor-β expression in rats［J］. Exp Ther Med, 2014, 7(6):1647-1652.
［20］ Sawaki D, Czibik G, Pini M, et al. Visceral adipose tissue drives cardiac aging through modulation of fibroblast senescence by osteopontin production［J］. Circulation, 2018, 138(8):809-822.
［21］ Jin T. Expression of osteopontin in myocardium of congenital heart disease［D］. Changsha: Central South University, 2010. (in Chinese)
金婷. 骨桥蛋白在先天性心脏病心肌中的表达及相关研究［D］.长沙：中南大学,2010.
［22］ Hou X, Fu M, Cheng B, et al. Galanthamine improves myocardial ischemia-reperfusion-induced cardiac dysfunction, endoplasmic reticulum stress-related apoptosis, and myocardial fibrosis by suppressing AMPK/Nrf2 pathway in rats［J］. Ann Transl Med, 2019, 7(22):634-643.
PDF(16382 KB)
