Relationship between fluctuating asymmetry of digit length and schizophrenia

LU Hong WANG Lu HUO Zheng-hao ZHAO Jun-li DANG Jie MA Zhan-bing

Acta Anatomica Sinica ›› 2020, Vol. 51 ›› Issue (5) : 792-795.

PDF(889 KB)
Welcome to visit Acta Anatomica Sinica! Today is Chinese
PDF(889 KB)
Acta Anatomica Sinica ›› 2020, Vol. 51 ›› Issue (5) : 792-795. DOI: 10.16098/j.issn.0529-1356.2020.05.025
Anatomy

Relationship between fluctuating asymmetry of digit length and schizophrenia

  • LU Hong1,2* WANG Lu3 HUO Zheng-hao1,2 ZHAO Jun-li4 DANG Jie1,2 MA Zhan-bing1
Author information +
History +

Abstract

Objective To investigate the relationship between the fluctuating asymmetry (FA) of digit length and schizophrenia in females from Ningxia Han nationality.  Methods The mean values and the differences of FA(2FA、3FA、4FA、5FA)and composite FA(CFA) of 292 individuals (controls:146; schizophrenia patients:146) were compared and analyzed by using anthropometry.   Results The result  showed the trend as 2FA > 4FA > 3FA > 5FA in both schizophrenia patients and controls; The mean values of each FA were higher in patients than those of in controls. There were significant differences in 2FA(P<0.01), 3FA, 4FA(all P<0.05)between the two groups. In schizophrenia patients, the number in FA≥0.04 mm of 2FA was significantly higher(P<0.01); There were no relationship between FA and the age at presentation of schizophrenia (P>0.05).   Conclusion FA of digit length, especially 2FA is correlated with schizophrenia in females from Ningxia Han nationality and may provide the important warning information for early diagnosis of the disease.

Key words

Digit length / Fluctuating asymmetry / Schizophrenia / Anthropometry / Female

Cite this article

Download Citations
LU Hong WANG Lu HUO Zheng-hao ZHAO Jun-li DANG Jie MA Zhan-bing. Relationship between fluctuating asymmetry of digit length and schizophrenia[J]. Acta Anatomica Sinica. 2020, 51(5): 792-795 https://doi.org/10.16098/j.issn.0529-1356.2020.05.025

References

[1] Palmer AR, Strobeck C. Fluctuating asymmetry analysis revisited. In: Polal M, ed. Development Stability: Causes and Consequences[M]. New York: Oxford University Press, 2003: 10-12.
[2] Larry JL, Christian PK. The genetics and evolution of fluctuating asymmetry [J]. Annu Rev Ecol Syst, 2005, 36(2):1-21.
[3] Lu H, Huo ZhH, Gao P, et al. Fluctuating asymmetry of dermatoglyphy in breast cancer patients[J ].Acta Anthropologica Sinica, 2009,40(1):37-40.(in Chinese)
陆宏,霍正浩,高平,等. 乳腺癌患者数量皮纹学特征的波动性不对称[J].解剖学报,2009,40(1):37-40.
[4] Dang J, Huo ZhH, Peng L, et al. Digital dermatoglyphics and fluctuating asymmetry of dermatoglyphics in schizophrenics[J].Chinese Journal of anatomy, 2015, 38(1):82-85.(in Chinese)
党洁, 霍正浩, 彭亮, 等. 精神分裂症患者数量皮纹学特征及其波动性不对称[J].解剖学杂志, 2015, 38(1):82-85.
[5] Arato M, Frecska E, Beck C, et al. Digit length pattern in schizophrenia suggests disturbed prenatal hemispheric lateralization, Prog. Neuro-Psychopharmacol [J]. Biol Psychiatry, 2004, 28(2): 191-194.
[6] Zeynep B, Paul WS, Randy JN, et al. Fluctuating asymmetry predicts human reactive aggression [J]. Am J Hum Biol, 2004, 16(12):458-469.
[7] Renee CF, Leigh WS, James MC, et al. Are body fluctuating asymmetry and the ratio of 2nd to 4th digit length reliable predictors of semen quality [J]? Hum Reprod, 2003, 18(4):808-812.
[8] Shen D, Yu HCh, Huo ZhH, et al. A study of fluctuating asymmetry of digit length in infertility [J]. Journal of Medieal Research, 2016, 45(8):32-36. (in Chinese)
沈丹,于皓臣,霍正浩,等.不育症患者指长波动不对称性特点的分析[J].医学研究杂志,2016,45(8):32-36.
[9] Li KK, Wang L, Yu HCh, et al. Fluctuating asymmetry of digit length in patients with gastric cancer[J]. Chinese Journal of Anatomy, 2018, 41(3):322-324.(in Chinese)
李可可,王璐,于皓臣,等.胃癌患者的指长波动性不对称[J].解剖学杂志,2018,41(3):322-324.
[10]Psychosis Branch of Chinese Medical Association. The Chinese classification and the diagnose criterion of mental disorder (CCMD-3)[M]. 3th, ed. Ji’nan: Shandong Technology Press, 2001: 47-76. (in Chinese)

中华医学会精神科分会.中国精神疾病分类方案与诊断标准第3版(CCMD-3)[M]. 第3版. 济南:山东科学技术出版社, 2001:47-76.

[11] Martin SM, Manning JT. Fluctuating asymmetry, relative digit length, and depression in men[J]. Evolution Hum Behav, 1999, 20 (1): 203-214.

[12] Lu H, Huo ZhH, Shi ZhY, et al. Fluctuating asymmetry of digit length in breast cancer patients[J ]. Acta Anatomica Sinica, 2012,43(1):149-151.(in Chinese)
陆宏,霍正浩,师志云,等. 乳腺癌患者指长波动性不对称[J].解剖学报,2012,43(1):149-151.
[13] Lu H, Dang J, Huo ZhH, et al. Relationship between fluctuating asymmetry o digit ratio and coronary heart disease[J]. Acta Anatomica Sinica, 2011, 42(2):109-111.(in Chinese)
陆宏, 党洁, 霍正浩,等. 指长波动性不对称与冠心病的相关性[J].解剖学报, 2011, 42(2):109-111.
[14] Van Oel CJ, Baare WF, HulshoffPol HE, et al. Differentiating between low and high susceptibility to schizophrenia in twins: the significance of dermatoglyphic indices in relation to other determinants of brain development[J].Schizophr Res,2001,52(2):181-193.
[15] Elvira B,Muriel W,Colm MC,et al.Dermatoglyphics and Schizophrenia:a meta-analysis and investigation of the impact of ovstetric complications upon a-b ridge count[J].Schizophr Res, 2005,72(3):399-404.
[16] Richard H. Introduction: fetal origins of postnatal health and disease[J].Early Hum Dev, 2005, 81 (2):721-722. 
[17] Zheng Z, Cohn MJ. Developmental basis of sexually dimorphic digit ratios[J].Proc Natl Acad Sei USA, 2011,108(39):16289-16294
[18] Arnold AP. The organizational-activational hypothesis as the foundation for a unified theory of sexual differentiation of all mammalian tissues[J]. Horm Behav, 2009, 55(2): 570-578.
[19] Hai R, Li KK, Fan B, et al. Study on digit ratio in females with schizophrenia[J]. Chinese Journal of Anatomy, 2019, 42 (1):68-70. (in Chinese)
海荣,李可可, 范斌,等.女性精神分裂症患者指长比的分析[J].解剖学杂志,2019,42 (1):68-70.
[20] Collinson SL, Lim M, Chaw JH, et al. Increased ratio of 2nd to 4th digit (2D∶4D) in schizophrenia[J]. Psychiatry Res, 2018, 176 (2): 8-12.
[21] Gooding DC, Johnson M, Peterman JS. Schizotypy and altered digit ratio: a second look[J]. Psychiatry Res, 2010, 30 (1): 73-78.
[22] Venkatasubramanian G, Arasappa R, Rao NP, et al. Digit ratio (2D:4D) asymmetry and Schneiderian first rank symptoms: implications for cerebral lateralisation theories of schizophrenia[J]. Laterality, 2011, 16 (3):499-512.
[23] Bunevicius MD, Tamasauskas PhD, Deltuva A, et al. Digit ratio (2D∶4D) in primary brain tumor patients: a caseV. P. -control study[J]. Early Hum Dev, 2016,103 (4):205-208.
[24] Lu W, Hong L, Li KK, et al. Digit ratio (2D:4D) in Chinese women with gastric cancer[J].Am J Hum Biol, 2018,e23109(1):1-3.
[25] Kerrie DS, Kayla JM, Devon NM. 2D:4D digit ratio predicts depression severity for females but not for malesr[J]. Pers Individ Dif, 2014,70 (3):136-139.
PDF(889 KB)

Accesses

Citation

Detail

Sections
Recommended

/