Progress in the therapeutic use of methylene blue in ischemic stroke

ZHANG Meng-qin LU Jian-fei CHEN Chun-hua*

doi:10.16098/j.issn.0529-1356.2019.05.023

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Acta Anatomica Sinica ›› 2019, Vol. 50 ›› Issue (5) : 677-683. DOI: 10.16098/j.issn.0529-1356.2019.05.023

Progress in the therapeutic use of methylene blue in ischemic stroke

ZHANG Meng-qin¹ LU Jian-fei² CHEN Chun-hua ^1*

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Abstract

Stroke has been widely studied as a highly lethal and highly disabling disease worldwide. Methylene blue approved by the Food and Drug Administration(FDA) of the United States has been used in the treatment of methemoglobinemia and cyanide poisoning for more than one hundred and twenty years. In recent studies, it has been found to have neuroprotective effects and is effective in a few of animal models of ischemic stroke. This article briefly reviews the recent research on the therapeutic use of methylene blue in ischemic stroke.

Key words

Methylene blue / Ischemic stroke / Neuroprotection

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ZHANG Meng-qin LU Jian-fei CHEN Chun-hua. Progress in the therapeutic use of methylene blue in ischemic stroke[J]. Acta Anatomica Sinica. 2019, 50(5): 677-683 https://doi.org/10.16098/j.issn.0529-1356.2019.05.023

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