Objective To observe the differences of somatotype, facial tissue profile between male and female of Han students, and the differences of facial tissue profile in homogeneous somatotype between male and female. Methods A total of 326 males and 478 females who were 18-23 years old with no disability, disease, deformity and no facial plastic history were studied. Somatotype was assessed by Heath-Carter method , and the angles of facial tissue profile were measured by FreeHand MX software. Results Han young males had central somatotype (3.52-3.28-3.40), and females with balanced endomorphy (4.52-3.03-3.23) that facial profile was to accord with esthetic Ricketts and Steiner plane. For total samples, it was negative correlation between height, body weight, tensive biceps girth, calf girth, humerus width and frontonasal angle, it was positive correlation between height and nasal tip angle, tensive biceps girth and nasolabial angle.It was negative correlation between height and mentolabial angle, between body weight, calf girth, endomorphic factor and fontonasal angle. It was positive correlation between ectomorphic factor and fontonasal angle for males homogeneous somatotype (P<0.05）. It was negative correlation betweenendomorphic factor and nasolabial angle.It was positive correlation between endomorphic factor and nasal tip angle for females homogeneous somatotype (P<0.05）. It was negative correlation between years of age and nasolabial angle for males and females, and mentolabial angle for females(P<0.05）. Conclusion Frontonasal angle is different between Han young students. It is different that somatotype influence soft tissue facial profile between Han young students. Frontonasal angle, nasal tip angle, lip convex angle are relative stable with years of age to change for Han young students.