
Role of microRNAs in liver regeneration
ZANG Xia-yan GENG Xiao-fang ZHANG Chun-yan XU Cun-shuan
Acta Anatomica Sinica ›› 2017, Vol. 48 ›› Issue (2) : 230-235.
Role of microRNAs in liver regeneration
microRNAs (miRNAs) are a group of endogenous, small, noncoding RNA molecules which can regulate gene expression at posttranscriptional level by binding to the 3’ untranslated regions (3’UTRs) of their target mRNAs. It has been reported that miRNAs regulated a variety of biological processes, including cell proliferation, differentiation, apoptosis, metabolic process,organ development,etc. Liver as one of the organs with extraordinary regenerative abilities, is considered to be an important material for the research of regeneration mechanism. This paper summarized the research advance of the role of microRNAs in liver regeneration.
[1]Mitchell C, Willenbring H. A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice[J]. Nat Protoc, 2008,3(7):1167-1170.
[2]Fausto N, Campbell JS, Riehle KJ. Liver regeneration[J]. Hepat, 2006,43(2):S45-S53.
[3]Szabo G, Bala S. MicroRNAs in liver disease[J]. Nat Struct Mol Biol, 2013,10 (9):542-552.
[4]Giordano S, Columbano A. MicroRNAs: new tools for diagnosis, prognosis, and therapy in hepatocellular carcinoma[J] Hepat, 2013,57(2):840-847.
[5]Wang XW, Heegaard NH, Orum H. MicroRNAs in liver disease[J]. Gastroenterology, 2012,142(7):1431-1443.
[6]Shu J, Kren BT, Xia Z, et al. Genomewide microRNA down-regulation as a negative feedback mechanism in the early phases of liver regeneration[J]. Hepat, 2011,54(2):609-619.
[7]Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function[J]. Cell, 2004,116(2):281-297.
[8]Kawamata T, Seitz H, Tomari Y. Structural determinants of miRNAs for RISC loading and slicer-independent unwinding [J]. Nat Struct Mol Biol, 2009,16(9):953-960.
[9]Ahmed F, Ansari HR, Raghava GP. Prediction of guide strand of microRNAs from its sequence and secondary structure[J]. BMC Bioinformatics, 2009,10(1):105-117.
[10]Chen K, Song F, Calin GA, et al. Polymorphisms in microRNA targets: a gold mine for molecular epidemiology[J]. Carcinogenesis, 2008,29 (7):1306-1311.
[11]Geiger T, Cox J, Ostasiewicz P, et al. Super-SILAC mix for quantitative proteomics of human tumor tissue[J]. Nat Methods, 2010,7(5):383-385.
[12]Geng X, Chang C, Zang X, et al. Integrative proteomic and microRNA analysis of the priming phase during rat liver regeneration[J]. Gene, 2016,575(2):224-232.
[13]Marquez RT, Wendlandt E, Galle CS, et al. MicroRNA-21 is upregulated during the proliferative phase of liver regeneration, targets Pellino-1, and inhibits NF-kappaB signaling[J]. AM J Phusiol-Gastr L, 2010,298 (4):G535-541.
[14]Jiang Z, Johnson HJ, Nie H, et al. Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex[J]. J Biol Chem, 2003,278(13):10952-10956.
[15]Fujita S, Ito T, Mizutani T, et al. miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism[J]. J Mol Biol, 2008,378(3):492-504.
[16]Loffler D, Brocke-Heidrich K, Pfeifer G, et al. Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer[J]. Blood, 2007,110(4):1330-1333.
[17]Zhou R, Hu G, Liu J, et al. NF-kappaB p65-dependent transactivation of miRNA genes following Cryptosporidium parvum infection stimulates epithelial cell immune responses[J]. PLoS Pathog, 2009,5(12):e1000681.
[18]Vinciguerra M, Sgroi A, VeyratDurebex C, et al. Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes[J]. Hepat, 2009,49 (4):1176-1184.
[19]Song G, Sharma AD, Roll GR, et al. MicroRNAs control hepatocyte proliferation during liver regeneration[J]. Hepat, 2010,51(5):1735-1743.
[20]Park TJ, Kim JY, Oh SP, et al. TIS21 negatively regulates hepatocarcinogenesis by disruption of cyclin B1-Forkhead box M1 regulation loop[J]. Hepat, 2008,47(5):1533-1543.
[21]Ng R, Song G, Roll GR, et al. A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration[J]. J Clin Invest, 2012,122(3):1097-1108.
[22]Yan-nan B, Zhao-yan Y, Li-xi L, et al. MicroRNA-21 accelerates hepatocyte proliferation in vitro via PI3K/Akt signaling by targeting PTEN[J]. Biochem Bioph Res Co, 2014,443(3):802-807.
[23]Li JJ, Chan WH, Leung WY, et al. MicroRNA-21 promotes proliferation of rat hepatocyte BRL-3A by targeting FASLG[J]. Genet Mol Res, 2015,14(2):4150-4160.
[24]Fornari F, Gramantieri L, Ferracin M, et al. MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma[J]. Oncogene, 2008,27 (43):5651-5661.
[25]Yuan Q, Loya K, Rani B, et al. MicroRNA-221 overexpression accelerates hepatocyte proliferation during liver regeneration[J]. Hepat, 2013,57 (1):299-310.
[26]John K, Hadem J, Krech T, et al. MicroRNAs play a role in spontaneous recovery from acute liver failure[J]. Hepat, 2014,60(4):1346-1355.
[27]Hyun J, Wang S, Kim J, et al. MicroRNA125b-mediated Hedgehog signaling influences liver regeneration by chorionic plate-derived mesenchymal stem cells[J]. Sci Rep, 2015,5:14135.
[28]Zhou J, Ju W, Wang D, et al. Down-regulation of microRNA-26a promotes mouse hepatocyte proliferation during liver regeneration[J]. PLoS One, 2012,7(4):e33577.
[29]Pan C, Chen H, Wang L, et al. Down-regulation of MiR-127 facilitates hepatocyte proliferation during rat liver regeneration[J]. PLoS One, 2012,7(6):e39151.
[30]Chen J, Wang M, Guo M, et al. miR-127 regulates cell proliferation and senescence by targeting BCL6[J]. PLoS One, 2013,8(11):e80266.
[31]Huen MS, Sy SM, van Deursen JM, et al. Direct interaction between SET8 and proliferating cell nuclear antigen couples H4-K20 methylation with DNA replication[J]. J Biol Chem, 2008,283(17):11073-11077.
[32]Ohtake Y, Maruko A, Ohishi N, et al. Effect of retinoic acid on transglutaminase and ornithine decarboxylase activities during liver regeneration[J]. Cell Biochem Funct, 2008,26(3):359-365.
[33]Khrapenko LI, Huang N, Swenson E, et al. The microRNA miR-181b is involved in extracellular matrix remodeling during hepatic regeneration following partial hepatectomy[J]. Gastroenterology, 2009,136(5):A789.
[34]Cirera-Salinas D, Pauta M, Allen RM, et al. Mir-33 regulates cell proliferation and cell cycle progression[J]. Cell Cycle, 2012,11(5):922-933.
[35]Lu S, Jiao H, Xu J, et al. Downregulation of IL6 Targeted MiR-376b may contribute to a positive IL6 feedback loop during early liver regeneration in mice[J]. Cell Physiol Biochem , 2015,37 (1):233-242.
[36]Qiu LP, Fan HX, Jin WS, et al. miR-122-induced down-regulation of HO-1 negatively affects miR-122-mediated suppression of HBV[J]. Biochem Bioph Res Co, 2010,398(4):771-777.
[37]Li N, Fu H, Tie Y, et al. miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells[J]. Cancer Lett, 2009,275(1):44-53.
[38]Chen H, Sun YM, Dong RQ, et al. Mir-34a is upregulated during liver regeneration in rats and is associated with the suppression of hepatocyte proliferation[J]. PLoS One, 2011,6(5): e20238.
[39]Yuan B, Dong RQ, Shi D, et al. Down-regulation of miR-23b may contribute to activation of the TGF-beta 1/Smad3 signalling pathway during the termination stage of liver regeneration[J]. Febs Lett, 2011,585(6):927-934.
[40]He WX, Niu ZY, Zhao SL, et al. Smad protein mediated transforming growth factor beta 1 induction of apoptosis in the MDPC-23 odontoblast-like cell line[J]. Arch Oral Biol, 2005,50(11):929-936.
[41]Yu ZY, Bai YN, Luo LX, et al. Expression of microRNA-150 targeting vascular endothelial growth factor-A is downregulated under hypoxia during liver regeneration[J]. Mol Med Rep, 2013,8(1):287-293.
[42]Salehi S, Brereton HC, Arno MJ, et al. Human liver regeneration is characterized by the coordinated expression of distinct microRNA governing cell cycle fate[J]. Am J Transplant, 2013,13(5):1282-1295.
[43]Lu CE, Zhang J, Nie ZM, et al. Study of microRNAs related to the liver regeneration of the whitespotted bamboo shark, chiloscyllium plagiosum[J]. Biomed Res Int, 2013,2013:795676.
[44]Chaveles I, Zaravinos A, Habeos IG, et al. MicroRNA profiling in murine liver after partial hepatectomy[J]. Int J Mol Med, 2012,29(5):747-755.
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