Mechanism of peripheral regulation of temperature in hot flushes of low estrogen

JIANG Hai ZHANG Jing WANG Wen-juan WANG Ke QIN Li-hua* BAI Wen-pei*

doi:10.16098/j.issn.0529-1356.2016.05.024

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Acta Anatomica Sinica ›› 2016, Vol. 47 ›› Issue (5) : 709-713. DOI: 10.16098/j.issn.0529-1356.2016.05.024

Review

Mechanism of peripheral regulation of temperature in hot flushes of low estrogen

JIANG Hai¹ ZHANG Jing¹WANG Wen-juan¹ WANG Ke¹QIN Li-hua ^1* BAI Wen-pei^2*

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Abstract

In recent years, hot flashes have become one of the main factors which bother work and life of the women with low estrogen for various reasons. It greatly influences their quality of life. The narrow of the hypothalamic temperature set point has been internationally recognized as a mechanism of hot flashes. Because of this, the regulation of body temperature is losing its balance. Previous studies pay more attention to the mechanism in the relationship between the reduction of estrogen and disorder in central nervous system, which lead to hot flash. However, it focuses less on its efferent pathway of thermoregulation. In this article, we review the mechanism of thermoregulation by peripheral nervous system in hot flashes of menopause from three main ways which are the regulation of sympathetic nervous system, the regulation of somatic nervous system and the endocrine activity of adrenal hormone and thyroid hormone.

Key words

Low estrogen / Hot flash / Low estrogen / Hot flash / Thermoregulation / Neuroregulation / Humoral regulation / Human

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JIANG Hai ZHANG Jing WANG Wen-juan WANG Ke QIN Li-hua BAI Wen-pei. Mechanism of peripheral regulation of temperature in hot flushes of low estrogen[J]. Acta Anatomica Sinica. 2016, 47(5): 709-713 https://doi.org/10.16098/j.issn.0529-1356.2016.05.024

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