Correlativity between digit ratio and acne vulgaris among Han population in Zhejiang province

TANG Ting-bing* YE Xian-cai FAN Xiao-wen CHEN Guang-ping WANG Xiao-qing CHEN Huan

doi:10.16098/j.issn.0529-1356.2016.05.021

PDF(191 KB)

Acta Anatomica Sinica ›› 2016, Vol. 47 ›› Issue (5) : 693-696. DOI: 10.16098/j.issn.0529-1356.2016.05.021

Anthropology

Correlativity between digit ratio and acne vulgaris among Han population in Zhejiang province

TANG Ting-bing ^1* YE Xian-cai² FAN Xiao-wen¹CHEN Guang-ping¹WANG Xiao-qing¹CHEN Huan³

Author information +

History +

Abstract

Objective To study if acne vulgaris (AV) correlates with the digit ratio among Han population in Zhejiang province. Methods Adopt direct measurement method was used to measure the digit length 2D to 5D of AV patients and healthy people among Han Population in Zhejiang Province with the electronic digital caliper. Levels of AV severity were determined according to the international classification. Results An analysis was made on the digit lengths of 261 AV patients (74.3% are female) and 381 healthy people (59.6% are female) aging from 18 to 25 years.2D∶4D and 3D∶4D of female AV patients were significantly lower than female healthy people（P＜0.01 or P＜0.05）.2D∶3D，2D∶5D，4D∶5D and 3D∶5D of AV patients group and healthy group were almost same. The ratio of all digits had not too much differences in male AV patients group and male healthy group. Conclusion The onset of AV among Female Han Population in Zhejiang Province correlates with their low ratios of 2D∶4D，3D∶4D.

Key words

Zhejiang / Digit ratio / Acne vulgaris / Direct measurement / Han population

Cite this article

EndNote

Ris (Procite)

Bibtex

Download Citations

TANG Ting-bing YE Xian-cai FAN Xiao-wen CHEN Guang-ping WANG Xiao-qing CHEN Huan. Correlativity between digit ratio and acne vulgaris among Han population in Zhejiang province[J]. Acta Anatomica Sinica. 2016, 47(5): 693-696 https://doi.org/10.16098/j.issn.0529-1356.2016.05.021

References

［1］Zhang XJ. Dermatology and Venereal Disease［M］.8th ed. Beijing: People’s Medical Publishing House (PMPH)，2013:175-177. (in Chinese)

张学军.皮肤性病学［Ｍ］.第8版.北京：人民卫生出版社，2013：175-177.

［2］Kaur J，Sehgal VK，Gupta AK，et al.A comparative study to evaluate the efficacy and safety of combination topical preparations in acne vulgaris［J］.Int J Appl Basic Med Res，2015,5(2)：106,110.

［3］Taylor M, Gonzalez M, Porter R. Pathways to inflammation: acne pathophysiology［J］.Eur J Dermatol,2011,21(3): 323-333.

［4］Thiboutot DM. Acne. An overview of clincal research findings［J］. Dermatol clin, 1997, 15(1)：97-109.

［5］Yu ZhJ，Lu J, Duan XS, et al.Expression of androgen receptor in lesions of patients with acne vulgaris［J］. China Journal of Leprosy and Skin Diseases，2008，24(6)：433-435.(in Chinese)

于中蛟, 陆洁，段昕所，等.痤疮患者皮损处雄激素受体的表达［J］.中国麻风皮肤病杂志，2008，24(6)：433-435.

［6］Zouboulis CC.Acne vulgaris.The role of hormones［J］.Der Hautarzt，2010，61(2)：4046-4049.

［7］Pang Y，He ChD，Liu Y，et al. Length of CAG repeat in exon l of the androgen receptor gene is associated with the development of acne［J］. Chinese Journal of Dermatology, 2008, 41(12): 796-799. (in Chinese)

庞莹，何春涤，刘勇，等. 雄激素受体基因第一外显子CAG重复序列长度多态性与痤疮的相关性［J］.中华皮肤科杂志,2008, 41(12): 796-799.

［8］Manning JT. Digit Ratio: A Pointer to Fertility, Behavior and Health［M］.London: Rutgers University Press,2002:1-141.

［9］Manning JT, Callow M，Bundred PE. Finger and toe ratios in humans and mice: implications for the aetiology of diseases influenced by HOX genes［J］. Med Hypotheses，2003，60(3)：340-343.

［10］Xi HJ，Zhao H， Li WH，et al. Primary analysis of current studies on the digit ratio［J］.Acta Anatomica Sinica，2012，43（4）：569-573.(in Chinese)

席焕久，赵红，李文慧，等. 对指长比研究现状的初步分析［J］.解剖学报，2012，43（4）:569-573.

［11］Loehlin JC，Mcfadden D，Medland SE，et al. Population differences in finger-length ratios: ethnicity or latitude ［J］ ? Arch Sex Behav，2006，35(6)：739-742.

［12］Breedlove SM. Minireview: organizational hypothesis: instances of the fingerpost［J］. Endocrinology，2010, 151(9):4116-4122.

［13］Manning JT. Resolving the role of prenatal sex steroids in the development of digit ratio［J］. Proc Natl Acad Sci USA, 2011,108(39):16143-16144.

［14］Dressler SG, Voracek M. No association between two candidate markers of prenatal sex hormones: digit ratios (2D∶4D and other) and fingerridge counts［J］.Dev Psychobiol,2011,53(1):69-78.

［15］Okten A, Kalyoncu M, Yaris N. The ratio of second-and fourth-digit lengths and congenital adrenal hyperplasia due to 21-hydroxylase deficiency［J］.Early Hum Dev，2002，70(1-2):47-54.

［16］Brown WM, Hines M, Fane BA, et al. Masculinized finger length patterns in human males and females with congenital adrenal hyperplasia［J］. Horm Behav,2002, 42(4): 380-386.［17］Chai XJ, Jacobs LF. Digit ratio predicts sense of direction in women［J］. PLoS One, 2012, 7(2): e32816.

［18］Berenbaum SA, Bryk KK, Nowak N, et al. Fingers as a marker of prenatal androgen exposure［J］. Endocrinology, 2009, 150(11): 5119-5124.

［19］Minto CL, Liao KL, Conway GS, et al. Sexual function in women with complete androgen insensitivity syndrome［J］. Fertil Steril, 2003, 80(1):157-164.

［20］Manning JT, Bundred PE, Newton DJ, et al. The second to fourth digit ratio and variation in the androgen receptor gene［J］. Evol Hum Behav,2003,24(6):399-405.

［21］Zhao B. Chinese Journal of Clinical Dermatology［M］. Nanjing:Jiangsu Science and Technology Press, 2009:1165-1166. (in Chinese)

赵辨.中国临床皮肤病学［M］.南京：江苏科学技术出版社，2009：1165-1166.

［22］Manning JT, Fink B. Digit ratio (2D∶4D), dominance, reproductive success, asymmetry, and sociosexuality in the BBC Internet Study［J］. Am J Hum Biol, 2008, 20(4):451-461.

［23］Bilgi? ?, Dogˇdu M, IslamogˇluGK, et al. The relationship between the second to fourth digit ratio and acne vulgaris［J］.J Eur Acad Dermatol Venereol,2014,28(10):1340-1343.

［24］Berenbaum SA. Effects of early androgens on sex-typed activities and interests in adolescents with congenital adrenal hyperplasia［J］.Horm Behav,1999,35(1):102-110.

［25］Abbott DH, Barnett DK, Bruns CM, et al. Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome ［J］? Hum Reprod Update, 2005,11(4):357-374.

［26］Ventura T, Gomes MC, Pita A, et al. Digit ratio (2D∶4D) in newborns:influencess of prenatal testosterone and maternal environment［J］.Early Hum Dev, 2013,89(2):107-112.