FGA等15个短串联重复序列在融水县苗族群体中的遗传学分析

周丽宁; 覃耀春; 徐林; 李松峰; 邓琼英; 龚继春

解剖学报 ›› 2008, Vol. 39 ›› Issue (5) : 683-687.

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FGA等15个短串联重复序列在融水县苗族群体中的遗传学分析

周丽宁^{1;覃耀春^{2 ;徐林^{1* ;李松峰^{1 ;邓琼英^{1; 龚继春¹}}}}}

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STUDY ON POLYMORPHISMS OF 15 STR LOCI IN MIAO ETHNIC GROUP OF RONGSHUI COUNTY IN GUANGXI PROVINCE

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Abstract

P>Objective To investigate the distribution patterns of 15 short tandem repeats (STR) loci (TPOX，TH01，CSF1PO，D19S433，vWA，D18S51，D5S818，FGA，D8S1179，D21S11，D7S820，D3S1358，D13S317，D16S539，D2S1338 ) in Miao ethnic group of Rongshui County in Guangxi Province. Methods The sodium citratedblood specimens were collected from 208 healthy unrelated Miao individuals (man: 102, female: 106) in Rongshui County in Guangxi Province, and then the DNAs from the samples were extracted by phynolchloroform technique. The DNAs were amplified by using AmpFlSTR IdentifilerTM PCR Amplification Kit, and finally the data were detected with 3100 Genetic Analyzer. Result Altogether 5.20 alleles and 11.62 genotypes of 15 STR were found in 208 healthy unrelated Miao individuals of Rongshui County in Guangxi Province. The allele frequency and genotype frequency were 0.004 8-0.466 3 and 0.004 8-0.317 3 respectively. Total discrimination power wa