刀豆蛋白A诱导大鼠小肠黏膜微血管内皮细  胞分泌IFN-γ的研究

尹龙SUB&gt;; SUB&gt;胡格 SUB&gt;; SUB&gt;索占伟; 段慧琴; 张涛; 穆祥

解剖学报 ›› 2007, Vol. 38 ›› Issue (4) : 486-488.

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刀豆蛋白A诱导大鼠小肠黏膜微血管内皮细胞分泌IFN-γ的研究

尹龙^{1SUB>; /SUB>胡格^{1 SUB>;/SUB>索占伟^{1;段慧琴^{1;张涛^{2;穆祥^1*}}}}}

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ConA INDUCES INTESTINAL MUCOUS MICROVASCULAR ENDOTHELIAL CELLS TO SECRETE IFN-γ

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Abstract

Objective To study whether ConA could induce microvascular endothelial cells to secrete IFN-γ. Methods IFN-γ was tested by double antibody sandwich ELISA. Results The microvascular endothelial cells of the intestinal mucous could be remarkably activated by ConA to secret IFN-γ, and the activations of 5\^0mg/L ConA was time_dependent,but the 10\^0 mg/L ConA was not so;There was not obviously different between the group of 5\^0mg/L ConA and that of 10.0 mg/L ConA . Conclusion ConA could induce microvascular endothelial cells of the rat intestinal m