转录因子环腺苷酸反应元件结合蛋白介导的细胞凋亡及其调控机制

李垒; 王萍.

doi:10.3969/j.issn.0529-1356.2012.01.026

解剖学报 ›› 2012, Vol. 43 ›› Issue (1) : 139-144. DOI: 10.3969/j.issn.0529-1356.2012.01.026

综述

转录因子环腺苷酸反应元件结合蛋白介导的细胞凋亡及其调控机制

李垒; 王萍*.

作者信息 +

Cell apoptosis mediated by the transcription factor cAMP response element binding protein and its regulatory mechanism

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Abstract

Cell apoptosis is a complex and precise adjustment process, which involves numerous signal proteins. cAMP response element binding protein(CREB), a transcriptional regulation factor in eucaryotic cell, regulates the cell apoptosis through changing the intracellular signal transduction by its phosphorylation, which is a pop research in recent years. In this review, recent progress in studying the regulatory effects of transcription factor CREB on cell apoptosis is briefly summarized.

导出引用

李垒;王萍.. 转录因子环腺苷酸反应元件结合蛋白介导的细胞凋亡及其调控机制[J]. 解剖学报. 2012, 43(1): 139-144 https://doi.org/10.3969/j.issn.0529-1356.2012.01.026

Cell apoptosis mediated by the transcription factor cAMP response element binding protein and its regulatory mechanism[J]. Acta Anatomica Sinica. 2012, 43(1): 139-144 https://doi.org/10.3969/j.issn.0529-1356.2012.01.026

中图分类号： R329