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人脑伏隔核的数字解剖
Digital anatomy of nucleus accumbens in the human brain
目的 探讨数字人脑中伏隔核的定位、参数测量及三维显示。方法 运用数控铣床完成1例45岁男性标本头部原始数据的采集，断面间距0.5mm。选取包含脑组织的连续横断面图像300幅，利用Photoshop CS软件完成尾状核、壳、伏隔核的图像分割，在重建的连续冠状断面图像上按照哈佛大学医学院的颅脑图像分割方法区分伏隔核，计算伏隔核体积及相关位置信息。利用Amira 3.1.1软件实现尾状核、壳、伏隔核的三维可视化。结果 伏隔核及其毗邻结构、常用伏隔核损毁靶点清晰显示。伏隔核体积左侧为972.5mm3，右侧为830.6mm3，左侧大于右侧。伏隔核质心三维坐标，左侧(-11.0, 24.4, 1.3)，右侧(9.3, 23.9, 1.7)。结论 伏隔核的数字解剖能够清晰显示伏隔核的形态，明确伏隔核的体积、位置及毗邻关系。
Objective To explore the locating, parameter measurement and 3D display of nucleus accumbens in human brain in terms of digital anatomy. Methods The raw data of the head specimen of a 45-year-old male adult with 0.5mm as the section spacing was collected by using digital milling machine. Three hundreds images of continual cross sections containing brain were chosen and the segmentation of the caudate nucleus, putamen and nucleus accumbens was accomplished with Photoshop CS. The nucleus accumbens on the images of continual coronal section reconstruction were distinguished according to Harvard Medical School’s segment method to calculate the volume of nucleus accumbens and collect the correlative location information. The caudate nucleus, putamen and nucleus accumbens were 3D visualize with the software of Amira 3.1.1. Results The nucleus accumbens, the adjoining structure and the lesion target of nucleus accumbens were all clearly visible. The left nucleus accumbens volume was 972.5mm3, and the right was 830.6mm3. The 3D coordinate value was the left (-11.0, 24.4, 1.3) and the right (9.3, 23.9, 1.7). Conclusion The digital anatomy of nucleus accumbens can distinctly display the nucleus accumbens, form and confirm it’s volume, location and adjoining area, which is useful to clinician.
Nucleus accumben / Brain / Sectional anatomy / Digital anatomy / Digital human
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颅脑的数字化研究
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