目的 探讨标本固化硬度与固化温度、固化时间的关系。方法 取福尔马林固定的人肌、肝、肺、肠、脑组织块各6件，经同一塑化流
程中处理，仅在固化过程中设置不同的固化温度-固化时间处理系列，检测标本固化硬度。结果 在固化过程中，各标本硬度随着时间的延长而
升高。固化第3天肝标本达到中等硬度，脑标本需7d，肺标本、肠标本和肌标本需14d。肝标本除在室温外，硬度均增加较快；脑标本在高温时
硬度增加较快；肌标本硬化2周内在各温度条件下硬度差别不明显，在硬化2周后，在高温时硬度均增加较快。肠和肺标本在各温度条件下硬度
差别不明显。结论 肝、肠、肺宜采用低温固化（室温、30℃），脑和肌肉需采用先低温固化（室温、30℃），然后高温固化（45℃、60℃）。

Objective To study the relationships between the hardness of specimen and curing temperature, and time. Methods
Thirty specimens of muscle, liver, lung, intestine and brain, 6 each were collected from formalin-fixed human cadavers and
processed with the same plastination procedure before curing. During the curing process, the specimens were placed in a sealed
chamber, exposed to Hoffen R6 gas and cured for 49 days at different temperature. Results During the curing process, the hardness
of specimens increased with time. The liver specimen had medium hardness in 3 days, and the brain in 7 days, and the lung,
intestine and muscle in 14 days. The hardness of the liver increased rapidly at 30℃，45℃，60℃ temperature. The hardness
of the brain specimen increased rapidly at high temperature. The obvious hardness difference of muscle specimen is not observed
in the curing of two weeks among different temperature conditions. After two weeks of hardening, the hardness of muscle increased
rapidly at high temperatures. No obvious hardness differences of the specimens of lung and intestine were observed in two weeks
during curing at different temperature conditions. Conclusion The low-temperature curing (at room temperature, 30℃) is better
for the specimens of liver, intestine, and lung . The specimens of brain and muscle require low temperature curing (at room
temperature, 30℃) at first, and then high temperature curing (45℃, 60℃).