Bcl-2在小鼠肾脏发生发育中的表达

宋小峰; 陈雪; 任昊; 翟效月

doi:10.3969/j.issn.0529-1356.2012.05.014

解剖学报 ›› 2012, Vol. 43 ›› Issue (5) : 658-661. DOI: 10.3969/j.issn.0529-1356.2012.05.014

组织学胚胎学发育生物学

Bcl-2在小鼠肾脏发生发育中的表达

宋小峰^{1,2; 陈雪^{1; 任昊^{1; 翟效月^1*}}}

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Expression of Bcl-2 during the development of mouse kidney

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Abstract

Objective To explore the expression of Bcl-2 during mouse kidney development. Methods Fifty-five Kunming mice from embryonic day 16(E16d), 18 and postnatal day 1(P1d), 3, 5, 7, 14, 21 were chosen to be used to investigate the expression of Bcl-2 on epoxy sections with immunohistochemistry technique and stereological methods. Results During mouse kidney development, the positive staining of Bcl-2 was mainly observed in proximal tubules. The increase with numerical area density(N A) of Bcl-2 was the fastest from E18d to P1d, while not much changed after P7 d. Conclusion During the pristine kidney development, the expression of Bcl-2 influences survival or death of proximal tubule.

导出引用

宋小峰;陈雪;任昊;翟效月. Bcl-2在小鼠肾脏发生发育中的表达[J]. 解剖学报. 2012, 43(5): 658-661 https://doi.org/10.3969/j.issn.0529-1356.2012.05.014

Expression of Bcl-2 during the development of mouse kidney[J]. Acta Anatomica Sinica. 2012, 43(5): 658-661 https://doi.org/10.3969/j.issn.0529-1356.2012.05.014

中图分类号： R329.1