目的  构建阿克苏地区维吾尔族成人握力参考标准，分析其相关影响因素，为该地区健康干预及肌肉减少症等疾病的评估提供科学依据。 方法  采用整群随机抽样法，对阿克苏地区成年维吾尔族 1123 例居民(男439 例、女684 例）进行握力、身高、体成分（全身肌肉量、全身脂肪量、体脂率、上肢肌肉量、下肢肌肉量)、人体测量学指标（腰围、臀围、腰臀比、手长、掌长、掌宽、手面积）等测量，通过Lambda-Mu-Sigma (LMS)法建立握力百分位数（P5、P25、P50、P75、P95）曲线，利用方差分析、独立样本 t 检验、 Person 偏相关、多元线性回归等方法，分析维吾尔族与不同人群间握力值的差异及该人群握力的影响因素,并与国内外人群进行比较。 结果  维吾尔族20~80岁人群握力性别与年龄差异显著（P<0.01），男性握力显著高于女性，且两性均在20~29岁达到峰值，50岁后明显下降。与国内外其他人群相较，维吾尔族握力水平总体处于中等偏下，男性显著低于白种人、黄种人及我国汉族人群，高于藏族及马来西亚人；女性亦呈相似趋势。偏相关分析显示，在男性中，年龄、体脂率与握力成负相关，而身高、体重、身体质量指数(BMI)、全身肌肉量、上肢肌肉量、下肢肌肉量、手长、掌宽、手面积均与握力成正相关。在女性中，年龄、体脂肪率、腰围及腰臀比与握力成负相关，身高、体重、BMI、全身肌肉量、上肢肌肉量、下肢肌肉量、手长、掌宽、手面积均与握力成正相关。多元线性回归分析发现，年龄、全身肌肉量对维吾尔族成年男性握力的影响有统计学意义（P<0.01）；年龄、全身肌肉量、腰臀比及掌宽对维吾尔族成年女性握力的影响有统计学意义（P<0.01）。 结论  建立了维吾尔族人群两性不同年龄段握力百分位参考值，年龄及全身肌肉量是该地区人群握力的核心影响因素，女性中腰臀比与掌宽也可分别独立影响握力。

 Objective  To establish reference standards for handgrip strength among Uyghur adults in the Aksu region and to analyze associated influencing factors, thereby providing scientific evidence for local health interventions and the assessment of sarcopenia-related conditions.  Methods  Using a cluster random sampling method, 1123 adult Uyghur residents (439 men and 684 women) in the Aksu region were assessed for handgrip strength, height, body composition (total muscle mass, total fat mass, body fat percentage, upper-limb muscle mass, lower-limb muscle mass), and anthropometric indicators (waist circumference, hip circumference, waist-hip ratio, hand length, palm length, palm width, and hand area). Percentile curves (P5, P25, P50, P75, P95) for handgrip strength were constructed using the Lambda-Mu-Sigma (LMS) method. ANOVA, independent-sample t-tests, Pearson partial correlation, and multiple linear regression were applied to examine differences in handgrip strength between Uyghurs and other populations, identify influencing factors, and compare values with domestic and international populations.  Results  Handgrip strength among Uyghurs aged 20-80 years showed significant differences by sex and age (P<0.01). Men had substantially higher grip strength than women, and both sexes reached peak values at ages 20-29, followed by a marked decline after age 50. Compared with other domestic and international populations, the overall grip strength level of Uyghurs was moderately low. Uyghur men had significantly lower values than Caucasian, East Asian, and Han Chinese populations, but higher than Tibetan and Malaysian populations; Similar trends were observed in women. Partial correlation analysis showed that in men, age and body fat percentage were negatively correlated with grip strength, while height, weight, body mass index (BMI), total muscle mass, upper-limb and lower-limb muscle mass, hand length, palm width, and hand area were positively correlated. In women, age, body fat percentage, waist circumference, and waist-hip ratio were negatively correlated with grip strength, whereas height, weight, BMI, total muscle mass, upper-limb and lower-limb muscle mass, hand length, palm width, and hand area were positively correlated. Multiple linear regression indicated that age and total muscle mass were significant predictors of grip strength in adult Uyghur men (P<0.01), while age, muscle mass, waist-hip ratio, and palm width were significant predictors in Uyghur women (P<0.01).   Conclusion  Reference percentile values for handgrip strength across different age groups and both sexes have been established for the Uyghur population. Age and total muscle mass are the primary determinants of grip strength in this population, while waist-hip ratio and palm width also independently influence grip strength in women.