机器人辅助肾移植的研究现状与展望

范婵媛 闵祥德 孙凯伦

解剖学报 ›› 2026, Vol. 57 ›› Issue (1) : 30-35.

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解剖学报 ›› 2026, Vol. 57 ›› Issue (1) : 30-35. DOI: 10.16098/j.issn.0529-1356.2026.01.005
机器人与手术导航专栏

机器人辅助肾移植的研究现状与展望

  • 范婵媛1闵祥德1孙凯伦2*
作者信息 +

Current status and future perspectives of robot-assisted kidney transplantation

  • FAN Chan-yuan1, MIN Xiang-de1, SUN Kai-lun2*
Author information +
文章历史 +

摘要

机器人辅助肾移植(RAKT)是一种新兴的微创肾移植术式,利用机器人辅助实施肾移植手术。与传统开放肾脏移植术(OKT)相比,RAKT术后并发症发生率更低,患者恢复更快,而移植后肾功能和肾存活率等疗效指标与开放手术相当。然而,RAKT的推广面临成本高昂、学习曲线长和缺乏高质量循证研究等挑战。未来,随着经验积累和技术进步,RAKT有望进一步应用并优化手术效果,成为肾移植领域的重要发展方向。

Abstract

Robot-assisted kidney transplantation (RAKT) is an emerging minimally invasive surgical technique that utilizes robotic systems to perform kidney transplantation. Compared with the conventional open kidney transplantation(OKT), RAKT is associated with a lower incidence of postoperative complications and faster postoperative recovery, while maintaining comparable outcomes with open surgery in graft function and graft survival. Despite these advantages, the widespread adoption of RAKT remains limited due to high equipment costs, a steep learning curve, and the lack of high-quality evidence from randomized controlled trials. With the accumulation of clinical experience and continued technological innovation, RAKT is expected to be further optimized and gradually extended to broader clinical settings. It holds promise as a valuable advancement in the field of kidney transplantation, offering a balance between surgical precision and minimally invasive benefits.

关键词

肾脏移植 / 微创手术 / 机器人辅助肾移植 /

Key words

Kidney transplantation;Minimally invasive surgery;Robot-assisted kidney transplantation / Human

引用本文

导出引用
范婵媛 闵祥德 孙凯伦. 机器人辅助肾移植的研究现状与展望[J]. 解剖学报. 2026, 57(1): 30-35 https://doi.org/10.16098/j.issn.0529-1356.2026.01.005
FAN Chan-yuan, MIN Xiang-de, SUN Kai-lun. Current status and future perspectives of robot-assisted kidney transplantation[J]. Acta Anatomica Sinica. 2026, 57(1): 30-35 https://doi.org/10.16098/j.issn.0529-1356.2026.01.005
中图分类号: R322    R445.2   

参考文献

[1]Zhang ZJ, Casiraghi F, Perkins GB, et al. Can mouse kidney transplant models inform mechanisms of injury and acceptance in clinical kidney transplantation?[J]. Am J Transplant, 2025, 25(7): 1391-1398.
[2]Basile G, Pecoraro A, Gallioli A, et al. Robotic kidney transplantation[J]. Nat Rev Urol, 2024, 21(9): 521-533.
[3]Ortved M, Dagnās-Hansen J, Stroomberg HV, et al. Open-label randomised clinical trial investigating whether robot-assisted kidney transplantation can reduce surgical complications compared to open kidney transplantation (ORAKTx): study protocol for a randomised clinical trial[J]. Trials, 2025, 26(1): 8.
[4]Territo A, Afferi L, Musquera M, et al. Robot-assisted kidney transplantation: the 8-year european experience[J]. Eur Urol, 2025, 87(4): 468-475.
[5]Ortved M, Dagnās-Hansen J, Stroomberg HV, et al. Introducing robot-assisted kidney transplantation in a high-volume centre in Denmark: a pilot and feasibility study[J]. J Robot Surg, 2025, 19(1): 45.
[6]Hoznek A, Zaki SK, Samadi DB, et al. Robotic assisted kidney transplantation: an initial experience[J]. J Urol, 2002, 167(4): 1604-1606.
[7]Giulianotti P, Gorodner V, Sbrana F, et al. Robotic transabdominal kidney transplantation in a morbidly obese patient[J]. Am J Transplant, 2010, 10(6): 1478-1482.
[8]Boggi U, Vistoli F, Signori S, et al. Robotic renal transplantation: first European case[J]. Transpl Int, 2011, 24(2): 213-218.
[9]Menon M, Sood A, Bhandari M, et al. Robotic kidney transplantation with regional hypothermia: a step-by-step description of the Vattikuti Urology Institute-Medanta technique (IDEAL phase 2a)[J]. Eur Urol, 2014, 65(5): 991-1000.
[10]Wang XN, Zu Q, Zhu Q, et al. Surgical outcomes of robotic-assisted kidney transplantation in end-stage renal disease treatment (1 case report)[J]. Journal of Minimally Invasive Urology, 2018, 7(3): 159-162. (in Chinese)
王昕凝, 祖强, 祝强, 等. 机器人辅助腹腔镜肾移植术1例报道并文献复习[J]. 微创泌尿外科杂志, 2018, 7(3): 159-162.
[11]Fan Y, Cai M, Fu YX, et al. Expert consensus on robot-assisted kidney transplantation[J]. Journal of Minimaly Invasive Urology, 2024, 13(2): 73-78. (in Chinese)
范阳, 蔡明, 付迎欣, 等. 机器人辅助腹腔镜肾脏移植术专家共识[J]. 微创泌尿外科杂志, 2024, 13(2): 73-78.
[12]Viguēs F, Etcheverry B, Perez Reggeti JI, et al. Orthotopic robot-assisted kidney transplantation: surgical technique and preliminary results[J]. Eur Urol, 2024, 85(6): 556-564.
[13]De Backer P, Van Praet C, Simoens J, et al. Improving augmented reality through deep learning: real-time instrument delineation in robotic renal surgery[J]. Eur Urol, 2023, 84(1): 86-91.
[14]Piana A, Gallioli A, Amparore D, et al. Three-dimensional augmented reality-guided robotic-assisted kidney transplantation: breaking the Limit of atheromatic plaques[J]. Eur Urol, 2022, 82(4): 419-426.
[15]Spinoit AF, Moreels N, Raes A, et al. Single-setting robot-assisted kidney transplantation consecutive to single-port laparoscopic nephrectomy in a child and robot-assisted living-related donor nephrectomy: initial Ghent experience[J]. J Pediatr Urol, 2019, 15(5): 578-579.
[16]Prudhomme T, Del Bello A, Sallusto F, et al. ABO-incompatible robotic-assisted kidney transplantation in the obese recipient[J]. Front Surg, 2020, 7: 49.
[17]Campi R, Pecoraro A, Li Marzi V, et al. Robotic versus open kidney transplantation from deceased donors: a prospective observational study[J]. Eur Urol Open Sci, 2022, 39: 36-46.
[18]Vignolini G, Campi R, Sessa F, et al. Development of a robot-assisted kidney transplantation programme from deceased donors in a referral academic centre: technical nuances and preliminary results[J]. BJU Int, 2019, 123(3): 474-484.
[19]Zhang HH, Ma M, Wu JP, et al. Early experience of robot assisted kidney transplantation[J]. Journal of Organ Transplantation, 2024, 45(2): 104-109. (in Chinese)
张浩涵, 马铭, 吴佳沛, 等. 经阴道机器人辅助肾移植1例报道及文献回顾[J]. 中华器官移植杂志, 2024, 45(2): 104-109.
[20]Kim SJJ, Kim S, Cho A, et al. Robot-assisted kidney transplantation: a propensity score-matched cohort analysis of early experience[J]. Int J Surg, 2024, 110(11): 7121-7133.
[21]Siena G, Campi R, Decaestecker K, et al. Robot-assisted kidney transplantation with regional hypothermia using grafts with multiple vessels after extracorporeal vascular reconstruction: results from the european association of urology robotic urology section working group[J]. Eur Urol Focus, 2018, 4(2): 175-184.
[22]Felip MM, Fardoun TA, Cusi LP, et al. Technique description and outcomes of robotic transvaginal-assisted living donor kidney transplantation[J]. Urol Int, 2021, 105(1-2): 148-154.
[23]Tsai MK, Lee CY, Yang CY, et al. Robot-assisted renal transplantation in the retroperitoneum[J]. Transpl Int, 2014, 27(5): 452-457.
[24]Ahlawat R, Sood A, Jeong W, et al. Robotic kidney transplantation with regional hypothermia versus open kidney transplantation for patients with end stage renal disease: an ideal stage 2B study[J]. J Urol, 2021, 205(2): 595-602.
[25]Karadag S, Eksi M, Ozdemir O, et al. Comparison of open and robot-assisted kidney transplantation in terms of perioperative and postoperative outcomes[J]. Int J Clin Pract, 2022, 2022: 2663108.
[26]Patil A, Ganpule A, Singh A, et al. Robot-assisted versus conventional open kidney transplantation: a propensity matched comparison with median follow-up of 5 years[J]. Am J Clin Exp Urol, 2023, 11(2): 168-176.
[27]Territo A, Boissier R, Subiela JD, et al. Prospective comparative study of postoperative systemic inflammatory syndrome in robot-assisted vs. open kidney transplantation[J]. World J Urol, 2022, 40(9): 2153-2159.
[28]Madhavan K, Jena R, Bhargava P, et al. Comparison of outcomes after open versus robotic kidney transplantation: a systematic review and meta-analysis[J]. Indian J Urol, 2023, 39(3): 186-194.
[29]Lee SW, Kim KS, Kim SH, et al. Predicting delayed postoperative length of stay following robotic kidney transplantation: development and simulation of perioperative risk factors[J]. Medicina (Kaunas), 2024, 60(8): 1255.
[30]Kiani AZ, Hill AL, Vachharajani N, et al. Robotic kidney transplant has superior outcomes compared to open kidney transplant: results of a propensity match analysis[J]. Surg Endosc, 2025, 39(1): 448-458.
[31]Pecoraro A, Andras I, Boissier R, et al. The learning curve for open and minimally-invasive kidney transplantation: a systematic review[J]. Minerva Urol Nephrol, 2022, 74(6): 669-679.
[32]Campi R, Pecoraro A, Vignolini G, et al. The first entirely 3D-printed training model for robot-assisted kidney transplantation: the RAKT box[J]. Eur Urol Open Sci, 2023, 53: 98-105.
[33]Pecoraro A, Territo A, Boissier R, et al. Proposal of a standardized training curriculum for open and robot-assisted kidney transplantation[J]. Minerva Urol Nephrol, 2024, 76(1): 110-115.
[34]Alip SL, Kim J, Rha KH, et al. Future platforms of robotic surgery[J]. Urol Clin North Am, 2022, 49(1): 23-38.
[35]Territo A, Mottrie A, Abaza R, et al. Robotic kidney transplantation: current status and future perspectives[J]. Minerva Urol Nefrol, 2017, 69(1): 5-13.
[36]Hameed AM, Yao J, Allen RDM, et al. The evolution of kidney transplantation surgery into the robotic era and its Prospects for obese recipients[J]. Transplantation, 2018, 102(10): 1650-1665.
[37]Eksi M, Sahin S, Evren I, et al. Can robot-assisted kidney transplantation provide higher quality of life than open kidney transplantation during the early postoperative period?[J]. Int J Clin Pract, 2021, 75(8): e14288.
[38]Slagter JS, Outmani L, Tran Ktck, et al. Robot-assisted kidney transplantation as a minimally invasive approach for kidney transplant recipients: A systematic review and meta-analyses[J]. Int J Surg, 2022, 99: 106264.
[39]Fan Y, Zhao J, Zu Q, et al. Robot-assisted kidney transplantation: initial experience with a modified hypothermia technique[J]. Urol Int, 2022, 106(5): 504-511.
[40]Machida Y, Iwai T, Kabei K, et al. Comparative analysis between insulated gel Bags and direct cooling for temperature management during kidney transplant vascular anastomosis[J]. J Clin Med, 2025, 14(7): 2368.

基金

国家自然科学基金青年科学基金(82400892)

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