目的 探讨在《组织学与胚胎学》教学中应用器官的组织构筑思维的可行性以及应用效果。 方法 在牡丹江医学院2017级临床专业中随机抽取4个班（共120人）作为研究对象，对照组采用以课堂讲授为主的传统教学法，实验组采用器官的组织构筑思维进行教学。教学结束后，对问卷调查和4个班学生的考试成绩进行分析。结果 实验组学习兴趣、创新能力、自学能力、动手能力、心理素质和团队意识的提升明显强于对照组（P＜0.01），实验组的考试成绩明显优于对照组(P<0.05)。结论 器官的组织构筑思维是一种非常适合组织学与胚胎学教学的新思维，该思维对于解决组织学与胚胎学教学中遇到的问题以及培养具有创新能力的高素质应用型医学人才具有重大作用。

Objective To explore the feasibility and effects of teaching with tissue construction thinking of organ in histology and embryology. Methods One hundred twenty students from four year 2017 clinical major classes in Mudanjiang medical university, who participated in the study of histology and embryology, were consecutively selected. Traditional teaching mode which is lecture-base learning was used in the control class，while the experimental class was taught by tissue construction thinking of organ,the evaluations were taken at the end，including questionnaires and exam scores of four classes. Results The experimental class was distinctly superior to the control class in learning interest, innovation ability, self-study ability, manipulative ability,psychological quality and team spirit (P＜0.01）, and in exam scores also (P＜0.05）. Conclusion Tissue construction thinking of organ is particulary adapted to the teaching of histology and embryology.The thinking can play a vital role in resolving the problems in teaching of Histology and embryology. And it will also help to cultivate high-quality applied medical talents with innovative ability.