目的 探索影响脑梗死功能结局的危险因素。 方法 回顾性分析594例脑梗死患者的临床资料，并与年龄、性别相匹配的351例健康者相对照。比较两组人口统计学、既往史和临床实验室指标，并采用非条件 logistic 回归进行多因素分析，了解影响脑梗死功能结局的危险因素。 结果 同型半胱氨酸、脂蛋白a、空腹血糖、入院时的收缩压和高血压史是影响脑梗死功能结局的独立危险因素。 结论 临床应及早控制引起脑梗死预后不良的危险因素，以减轻、防止不良的功能结局和预防脑梗死的再发。

Objective To explore the risk factors that affect the outcome of cerebral infarction. Methods The clinical data of 594 patients with cerebral infarction were retrospectively analyzed, and 351 healthy subjects matched with age were compared. Two groups of demographic, past history and clinical laboratory indicators were compared, and multivariate analysis was performed using non-conditional logistic regression to rebeal the risk factors that affect the outcome of cerebral infarction. Results Homocysteinemia level, lipoprotein(a) level, fasting blood glucose level, admission systolic blood pressure and hypertension history were the independent risk factors affecting the outcome of cerebral infarction. Conclusion The risk factors for the poor prognosis of cerebral infarction should be controlled early, so as to reduce and prevent the poor outcome and cerebral infarction recurrence.