颈椎曲度改变的眩晕患者危险因素分析

王英 殷闯 徐建可 尉娜 谭军*

doi:10.16098/j.issn.0529-1356.2018.05.013

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解剖学报 ›› 2018, Vol. 49 ›› Issue (5) : 641-645. DOI: 10.16098/j.issn.0529-1356.2018.05.013

解剖学

颈椎曲度改变的眩晕患者危险因素分析

王英¹ 殷闯² 徐建可³ 尉娜² 谭军^2*

作者信息 +

Analysis of the risk factors of vertigo in the patient with the change of cervical curvature

WANG Ying¹ YIN Chuang² XU Jian-ke³ WEI Na² TAN Jun ^2*

Author information +

文章历史 +

摘要

目的分析合并颈椎生理曲度改变的中青年眩晕患者的相关危险因素。方法收集2016年6月～2017年3月在新乡医学院第三附属医院神经内科住院的中青年眩晕患者病历，共78例，其中男性32例，女性46例。根据是否有颈椎生理曲度改变分为颈椎生理曲度正常组（n=22）和颈椎生理曲度异常组（n=56），比较两组的既往病史、实验室检查，对结果进行统计学分析。结果空腹血糖（FBG）、糖化血红蛋白（HbA1c）、同型半胱氨酸（HCY）、吸烟史及职业组间差异有显著性（P＜0.05）；性别、年龄在两组之间差异无显著性（P＞0.05）。结论合并颈椎生理曲度改变的中青年眩晕患者中FBG、HbA1c、HCY、吸烟史、糖尿病及职业是常见的危险因素。

Abstract

Objective To analyze the risk factors of vertigo in young and middle-aged patients with cervical curvature changes. Methods From June 2016 to March 2017, 78 young patients (32 males and 46 females) with vertigo were collected in the department of neurology of the third affiliated hospital of Xinxiang. The patients were divided into normal cervical curvature group (n=22) and abnormal cervical curvature group(n=56).The medical history and laboratory examination were compared between the two groups and were statistically analyzed. Results There were significant differences in fasting blood glucose (FBG), glycated hemoglobin (HbA1c), homocysteine (Hcy), smoking, diabetes, homocy steinemia and occupation between the two groups (P<0.05). There was no significant difference in gender and age between the two groups (P>0.05). Conclusion FBG, HbA1c, Hcy, smoking, diabetes and occupation are the common risk factors in young and middle-aged patients of vertigo with cervical curvature changes.

导出引用

王英殷闯徐建可尉娜谭军. 颈椎曲度改变的眩晕患者危险因素分析[J]. 解剖学报. 2018, 49(5): 641-645 https://doi.org/10.16098/j.issn.0529-1356.2018.05.013

WANG Ying YIN Chuang XU Jian-ke WEI Na TAN Jun. Analysis of the risk factors of vertigo in the patient with the change of cervical curvature[J]. Acta Anatomica Sinica. 2018, 49(5): 641-645 https://doi.org/10.16098/j.issn.0529-1356.2018.05.013

参考文献

［1］ Zhao G, Han JL,Cui LY. Expert consensus on diagnosis and treatment of vertigo［J］. Chinese Journal of Neurology, 2010,43(5):369-374.(in Chinese)

赵钢，韩军良，崔丽英.眩晕诊治专家共识［J］.中华神经科杂志，2010,43(5):369-374.

［2］ Yao RZh, Wang BW, Zhang JH, et al, Study on the ｒelationship between the degree change of cervical physiological curvatureand cervical spondylosis［J］. Acta Academiae Medicinae Weifang, 2017, 39(1): 16-18. (in Chinese)

姚汝瞻,王炳武,张金虎,等.颈椎生理曲度改变程度与颈椎病发病的关系［J］. 潍坊医学院学报,2017,39(1): 16-18.

［3］ Tsivgoulis G, Vadikolias K, Heliopoulos Ⅰ, et al. Prevalence of symptomatic intracranial atherosclerosis in caucasians: a prospective, multicenter, transcranial Doppler study［J］. J Neuroimaging,2014,24(1):11-17.

［4］ Wong KS, Ng PW, Tang A, et al. Prevalence of a symptomatic intracranial atherosclerosis in high-risk patients［J］. Neurology, 2007，68（23）:2035-2038.

［5］ Kim DE, Lee KB, Jang IM, et al. Associations of cigarette smoking with intracranial atherosclerosis in the patients with acute ischemic stroke［J］. Clin Neurol Neurosurg, 2012,114(9):1243-1247.

［6］ Oda K, Tanaka N, Arai T,et al. Polymorphisms in pro-and anti-inflammatory cytokine genes and susceptibility to atherosclerosis: a pathological study of consecutive autopsy cases［J］. Hum Mol Genet,2007, 16(6):592-599.

［7］ Lopez-Cancio E, Galan A, Dorado L, et al. Biological signatures of asymptomatic extra-and intracranial atherosclerosis: the Barcelona-As IA (Asymptomatic Intracranial Atherosclerosis) study［J］. Stroke,2012,43(10):2712-2719.

［8］ Zhao HY, Li YL. Mechanism discussion of vascular endothelial injury［J］. Medical Innovation of China, 2014,11(9): 137-139. (in Chinese)

赵恒懿，李运伦.血管内皮损伤的机制探讨［J］.中国医学创新,2014,11(9): 137-139.

［9］ Lai B, Wei YJ, Liu HL. Cigarette smoking endothelial dysfunction and atherosclerosis［J］. Chinese Heart Journal, 2015,27(4): 483-485. (in Chinese)

赖斌，魏玉杰，刘惠亮.吸烟、内皮细胞功能紊乱和动脉粥样硬化［J］.心脏杂志，2015,27(4): 483-485.

［10］Lü DY, Wang GM, Han X, et al. The effect of homocysteine on the expression of HCY-2 and cell proliferation in human aortic smooth muscle cells ［J］. Acta Anatomica Sinica, 2006,37(4):417-420. (in Chinese)

吕丹瑜,王光明,韩骁,等.同型半胱氨酸对人主动脉平滑肌细胞HCY-2表达及细胞增殖的影响［J］.解剖学报,2006,37(4):417-420.

［11］Bao XM,Lu GP. Vascular endothelial injury induced by hyperhomocysteinemia and early atherosclerosis［J］.Medical Recapitulate, 2009,15(2): 191-193. (in Chinese)

鲍晓梅,陆国平.高同型半胱氨酸血症致血管内皮损伤与早期动脉粥样硬化［J］.医学综述，2009,15(2): 191-193.

［12］Dai XH. Color Doppler ultrasonography in the diagnosis of vertebral artery insufficiency in patients with cervical spondylosis［J］. Journal of Jianghan University(Natural Sciences), 2006,34(3): 53-54．(in Chinese)

戴旭辉．颈椎病患者椎动脉供血不足的彩色多普勒超声检查［J］.江汉大学学报(自然科学版),2006,34(3): 53-54．

［13］Wu MX, Chen XH, Chen M. Application and comparison between CDFI and 3D CE MRA indiagnosing vertebral arterial insufficiency of diabetes mellitus［J］. Chinese Journal of Medical Imaging Technology, 2008,24(1): 63-65．(in Chinese)

吴明晓，陈秀华，陈敏．彩色多普勒超声与三维增强磁共振血管成像在糖尿病椎基底动脉供血不足患者诊断中的应用比较［J］.中国医学影像技术，2008,24(1): 63-65．

［14］Xue B,Yang J. Research progress and clinical application of vestibular evoked myogenic potentials［J］. Journal of Clinical Otorhinolaryngology, 2006,20(16): 764-766. (in Chinese)

薛彬,杨军.前庭诱发肌源性电位的研究进展和临床应用［J］. 临床耳鼻咽喉科杂志，2006,20(16): 764-766.

［15］Al-Sebeih K, Zeitouni A. Vestibular-evoked myogenic potentials as a test of otolith function ［J］.Med Princ Pract,2002,11(3):136-140.

［16］Murofushi T, Halmagyi GM, Yavor RA. Absent vestibular evoked myogenic potentials in vestibular neurolabyrinthitis. An indicator of inferior vestibular nerve involvement ［J］. Arch Otolaryngol Head Neck Surg, 1996,122(8):845-848.

［17］Colebatch JG, Halmagyi GM, Skuse NF. Myogenic potentials generated by a click-evoked vestibulocollic reflex ［J］. Neurol Neurosurg Psychiatry,1994,57(2):190-197.

［18］Didier A, Cazals Y. Acoustic responses recorded from the saccular bundle on the eighth nerve of the guinea pig ［J］. Hear Res,1989,37(2):123-127.