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不同分化阶段诱导性多能干细胞移植实验研究进展
Transplantation studies of induced pluripotent stem cells at different differentiated stages
Induced pluripotent stem cells (iPSCs) which derived from reprogrammed somatic cells, are totipotential cells similar to embryonic stem cells. Recently, iPSCs technology has been promptly improved in methods of induction and in vitro differentiation. Consequently, iPSCs at different differentiated stages have been widely studied in cell transplantation experiments. Here, we summarize the current studies of iPSCs transplantation, and reviewe some novel methods comparing with the older one. We propose that some problems need to be resolved before iPSCs could be applied in clinic therapy.
induced pluripotent Induced pluripotent stem cell / Blastocyst complementation / Organ bud
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