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颅脑正中矢状面磁共振成像对正常成人颅腔面积的测量
A quantitative study of cranial cavity area on mid-sagittal MR images from normal adults
目的 于磁共振正中矢状位成像测量正常成年人颅腔面积，并归纳正常值范围，探讨其与年龄的相关性及性别差异。方法 从我院图片存档与通信系统（PACS）随机选取发育正常、无相关疾病成年人720例，按不同年龄段分为6组：20～29岁组、30～39岁组、40～49岁组、50～59岁组、60～ 69岁组、70～79岁组, 每组120例，男女各60例。于磁共振正中矢状位T1加权像上测量幕上面积、幕下面积、全颅面积及幕上/幕下面积比值（简称幕上下比），并对所测得数据进行统计学分析。结果 正常成年人幕上面积、全颅面积、幕上下比随着年龄增加略增大，与年龄成弱正相关、线性回归关系；幕下面积随着年龄增加略减小，与年龄成弱负相关、线性回归关系。男性与女性幕上面积、幕下面积、全颅面积、幕上下比差异均有显著性（相应t值分别为t=11.55；t=15.69；t=14.70；t=-4.13，P值均<0.05），除了幕上下比外，余各测量值的均值均为男性大于女性。 结论 正常成年人颅腔正中矢状位磁共振成像颅腔面积各测量值参考值范围具有一定的变化规律，可以作为临床评价颅腔容积的指标之一。
Objective To measure the area of the cranial cavity on mid-sagittal magnetic resonance images (MRI) from normal adults, to determine its normal range and to investigate the correlation between the area and age, and its gender difference. Methods A total of 720 normal adults (without diseases associated with the head) were selected stochastically from the PACS of our hospital. The subjects were divided into 6 age groups: 20-29, 30-39, 40-49, 50-59, 60-69, and 70-79 years old. There were 120 subjects per age group with 60 males and 60 females. The areas of the supratentorial, subtentorial, whole cranial cavity and the supratentorial to the subtentorial cranial area ratio of the participant on mid-sagittal MRI were measured. The results were statistically analyzed. Results A slightly positive linear correlation was observed among the areas of the supratentorial, whole cranial cavity and the supratentorial to the subtentorial cranial area ratio and the age. A slightly negative linear correlation was observed between the areas of the subtentorial cranial cavity and the age. The means of the supratentorial, subtentorial, whole cranial cavity and the supratentorial to the subtentorial cranial area ratio were significantly different in different sexes（t=11.55；t=15.69；t=14.70；t=-4.13，all P<0.01）. All the measurements was larger in men than in female except for the ratio of the supratentorial to subtentorial cranial areas. Conclusion The reference ranges of all participants in normal adults on mid-sagittal MRI are regular, which can be used in clinic to evaluate the cranial cavity as one indicator.
Cranial cavity area / Magnetic resonance imaging / Adult human
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